TOWARDS A VERSATILE SYSTEM FOR ADVANCED NEURONAL RECORDINGS USING SILICON MULTISITE MICROELECTRODES.

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Abstract
INTRODUCTION The current understanding of how the nervous system functions is based on numerous observations of the behaviour of single units or a small ensemble of units correlated to some external stimulation or behavioural event [1]. However, the processing power of the nervous system lies in its network and interconnections [2]. Thus, the key to understand the nervous system is to make simultaneous observations of the activity of numerous cells forming acting and responding networks [3-5]. The obviously resulting need for a high number of extracellular recording sites placed in close proximity to those cells within the brain is a well know fact [6]. However, even the most up-to-date techniques are still depending on the use of singular microelectrodes or micro-wires to be implanted into the brain area under observation [7]. The use of bundled (stereo-or tetrodes) or brush-like arranged microelectrode-arrays helps to increase the number of recording sites, however, long and tedious implantation surgeries are still mandatory [8]. It appears therefore highly desirable to increase the productivity of a single surgery by implanting a multitude of recording sites at once [9]. Our project VSAMUEL set out to bring current micro-machining technologies to work and to produce not only batch

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