PROLIFERATIVE EFFECT OF LITHOCHOLIC ACID ON RAT-LIVER CELL IN CULTURE
- 1 January 1979
- journal article
- research article
- Vol. 31 (7) , 207-209
Abstract
In contrast to cholic acid, deoxycholic acid and chenodeoxycholic acid, lithocholic acid (LCA) enhances the growth of rat liver cells in culture. Enhanced proliferation of LCA-treated rat liver cells persists even 12 days after LCA was removed. These findings suggest a mutagenic effect of LCA, or a LCA metabolite, on rat liver cells.This publication has 8 references indexed in Scilit:
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