Histone Synthesis in vitro by Cytoplasmic Microsomes from HeLa Cells
- 21 March 1969
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 163 (3873) , 1351-1353
- https://doi.org/10.1126/science.163.3873.1351
Abstract
HeLa cell microsomes incorporate labeled amino acids in vitro into acid-soluble proteins which have the same electrophoretic mobility as histones isolated from the purified HeLa cell nuclei. The capacity to synthesize histones in vitro is dependent on deoxyribonucleic acid synthesis in the cells from which the microsomal fraction is prepared.Keywords
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