C-Reactive Protein and Risk of Cardiovascular Disease in Men and Women From the Framingham Heart Study

Abstract
Traditional risk factors for coronary heart disease (CHD) and cardiovascular disease (CVD) have been shown to effectively predict vascular disease events.1-3 Age, sex, blood pressure, total cholesterol level, high-density lipoprotein cholesterol (HDL-C) level, and cigarette smoking have been considered key factors to assess risk of vascular disease, using continuous or categorical variables. In addition, type 2 diabetes mellitus is highly related to CVD risk, and disease management guidelines in the United States now consider this diagnosis a coronary disease risk equivalent because it augments vascular disease risk so markedly.4,5

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