Late reactivation of spinal tuberculosis by low-dose methotrexate therapy in a patient with rheumatoid arthritis
Open Access
- 1 March 2001
- journal article
- research article
- Published by Oxford University Press (OUP) in Rheumatology
- Vol. 40 (3) , 341-342
- https://doi.org/10.1093/rheumatology/40.3.341
Abstract
Sir, It is generally accepted that the use of chronic corticosteroid treatment predisposes to primary tuberculosis (TB) and reactivation of TB infection [1], and most of the TB cases reported in rheumatoid arthritis (RA) and other rheumatic diseases are associated with the use of long‐term corticosteroid therapy [2]. A handful of cases of primary TB associated with the use of low‐dose methotrexate (MTX) have been reported in patients with psoriasis [3]. We believe, however, that ours is the first case of TB reactivation associated with low‐dose MTX therapy alone in a patient with RA.Keywords
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