Newcastle disease
- 1 March 2001
- journal article
- research article
- Published by Taylor & Francis in British Poultry Science
- Vol. 42 (1) , 5-22
- https://doi.org/10.1080/713655022
Abstract
1. In this paper several historical and contemporary aspects of Newcastle disease (ND) are reviewed, with particular reference to the greater understanding which modern techniques have allowed. 2. Virulent ND viruses were generally thought to have emerged in 1926 as a result of transfer from a wild bird host reservoir but there is evidence that the virulent virus may have existed in poultry before 1926. Recent findings suggest that the virulent virus may emerge in poultry as a result of mutations in viruses of low virulence. 3. The history of ND in Great Britain reflects the four known panzootics that have occurred and serves as a model for the impact this disease may have on poultry populations. 4. Attempts to control and eradicate ND are not as straightforward as it may appear; in particular vaccination, while preventing deaths and disease, on challenge may not prevent virus replication and could therefore lead to the virulent virus becoming endemic. 5. Village chickens are extremely important assets in most developing countries, representing a significant source of protein in the form of eggs and meat but endemic ND can cause mortality of up to 60% in village chickens.Keywords
This publication has 49 references indexed in Scilit:
- Excretion of pathogenic Newcastle disease virus by double‐crested cormorants (Phalacrocorax auritus) in absence of mortality or clinical signs of diseaseAvian Pathology, 1998
- Antigenic and phylogenetic studies on a variant Newcastle disease virus using anti‐fusion protein monoclonal antibodies and partial sequencing of the fusion protein geneAvian Pathology, 1998
- Antigenic diversity and similarities detected in avian paramyxovirus type 1 (Newcastle disease virus) isolates using monoclonal antibodiesAvian Pathology, 1997
- The epidemiology of Newcastle disease in rural poultry: A reviewAvian Pathology, 1994
- Evaluation of the molecular basis of pathogenicity of the variant Newcastle disease viruses termed ?pigeon PMV-1 viruses?Archiv für die gesamte Virusforschung, 1994
- Deduced amino acid sequences at the fusion protein cleavage site of Newcastle disease viruses showing variation in antigenicity and pathogenicityArchiv für die gesamte Virusforschung, 1993
- Characterization of French avian paramyxovirus type 1 (PMV 1) isolates with a panel of monoclonal antibodies to the Ploufragan strain of Newcastle disease virusArchiv für die gesamte Virusforschung, 1989
- Isolation of an antigenically unusual paramyxovirus type 1 from chickensAvian Pathology, 1988
- Antigenic variation of Newcastle disease virus strains detected by monoclonal antibodiesArchiv für die gesamte Virusforschung, 1983
- Molecular basis of infectivity and pathogenicity of myxovirusArchiv für die gesamte Virusforschung, 1979