Serological studies on chinese Kala Azar

Abstract
Both normal serum and that of Kala Azar patients immobilized and destroyed the great majority of flagellates in cultures of Chinese Leishmania. This power is destroyed by inactivating the serum. Employing as antigen an alcoholic suspension of the spleen and liver of hamsters infected with Leishmania, the authors obtained a well-marked deviation of the complement in the sera of 19 out of 24 Chinese patients infected with Kala Azar. Out of 57 controls, 6 also showed deviation; 5 of these gave strongly positive Wassermann reactions, while 1 contained anti-complement.

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