Biocompatibility Studies with a Novel Perfluorochemical Emulsion

Abstract
Biocompatibility studies with a novel perfluorochemical (PFC) emulsion have been performed in rats. Injection of the emulsion was followed by changes in lymphoid tissue weights, comparable but not identical to those produced by the commercial formulation, Fluosol- DA 20% (F-DA). Peritoneal injection of either the novel emulsion or F-DA enhanced the humoral immune response to intraperitonally-injected sheep red blood cells (SRBC) suggesting immunopotentiating properties of emulsion components.

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