SARS — Looking Back over the First 100 Days

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Abstract
Each winter, a number of surveillance networks are put in place to detect unusual outbreaks of severe respiratory disease. Last winter, although there had been some minor activity, nothing serious came up until late February 2003, when Dr. Carlo Urbani alerted the World Health Organization (WHO) that there was a novel form of severe pneumonia at a hospital in Hanoi, Vietnam. The pneumonia had a peculiar hallmark: health care workers were being stricken at an alarming rate. With this key observation and many negative diagnostic tests for known pathogens, it became clear that we had a new disease, severe acute respiratory syndrome (SARS), on our hands.

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