Die Lipoide einiger Gewebe und Organe des Menschen

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Abstract
The following results were obtained from (skeletal, cardiac and uterus muscle; hypophyses, adrenal glands, testes and ovaries): (1) The total lipid content is 2-3% of the fresh weight (exception: adrenals, 18%). Except in skeletal and cardiac muscle, the neutral lipids contain 30-50% cholesterol, while the content of cholesterol esters (adrenals 98%) and free cholesterol (uterus muscle 97%) shows strong variations. The glycerophosphatide and plasmalogen contents are 2-3 times higher in cardiac muscle (1. 8% of fresh weight or 6. 9 [mu] [image]/g fresh weight) and adrenals (1. 9% of fresh weight or 3. 5 [mu] [image]/g fresh weight) than in other organs. The fatty acid mixtures from the glycerophosphatides of all organs are characterized by their content of polyenoic acids (38-53% of the total fatty acids). Especially notable is the linoleic acid content (30 and 20%) of the glycerophosphatides of skeletal and cardiac muscle, respectively; also, the high proportion of C22-polyenoic acids in testes and hypophyses (14. 7 and 12. 8% of the total fatty acids, respectively). The aldehyde mixture from the plasmalogens of the organs studied contains 90-98% C16- and C18-aldehydes. The high content of C18-monoenoic aldehyde (15-30% of the total aldehyde) is striking. Polyenoic aldehydes do not occur to any appreciable extent. The occurrence of aldehydes with longer carbon chains than Cl8 is notable; for the first time, a C20-monoenoic aldehyde and traces of a C22-aldehyde were detected. Branched chain aldehydes only represent 2-5% of the total aldehydes.

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