THE OXYGEN CONSUMPTION OF GUINEA-PIG TISSUES IN VARIOUS MEDIA

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Abstract
The QO2 of various guinea-pig tissues was observed in phosphate buffered NaCl and Ringer''s soln. and in bicarbonate-free horse serum, with and without added glucose, and with varying concs. of PO4. The QO2 of testis was about the same in all media. That of kidney, heart and liver was higher in serum than in either NaCl or Ringer''s soln., the elevation being approximately 30, 35-60, and over 100% respectively. The QO2 of brain, on the. other hand, was about 50% higher in the salt media than in serum, which was not to be accounted for by lack of substrate in the latter. This and other considerations suggested a qualitative distinction between the oxidative systems of brain and those of other, non-nervous tissues.

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