A NEW GERMICIDE FOR USE IN THE GENITO-URINARY TRACT: "MERCUROCHROME-220"
Open Access
- 15 November 1919
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 73 (20) , 1483-1491
- https://doi.org/10.1001/jama.1919.02610460001001
Abstract
During the past two years the research work in the laboratories of the James Buchanan Brady Urological Institute has been given over largely to the study of antiseptics with a view particularly to the development of drugs applicable to the genito-urinary tract. Attention was first directed to internal antiseptics, since Hinman1had previously shown in our laboratories the questionable value of hexamethylenamin. Starting with the remarkable selective activity of the kidneys on phenolsulphonephthalein, as shown by the work of Abel and Rowntree2and developed as a functional test in our clinic, we tried to attach other chemical agents to phenolsulphonephthalein and thus produce an effective internal urinary antiseptic. Some interesting drugs were produced and studied by Davis and one of us (E. C. W.3). The war interrupted these studies, but the urgent need of really effective antiseptics for local use in the genito-urinary tract induced us laterKeywords
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