A genetic map of several mutations affecting the mucopeptide layer ofEscherichia coli
- 1 August 1972
- journal article
- research article
- Published by Hindawi Limited in Genetics Research
- Vol. 20 (1) , 65-74
- https://doi.org/10.1017/s0016672300013598
Abstract
SUMMARY: Several temperature-sensitive mutants ofEscherichia coliwere isolated which lyse at the restrictive temperature. Some of these possess a biochemically defined lesion in cell-wall mucopeptide synthesis. Three genes, termedmurC, EandF, have been localized between theaziandleumarkers. From transductional data a fine structure map was constructed of themurmutations, establishing the order of the genes. The genetic relationship between these cell wall genes and neighbouring genes involved in cell division is discussed.Keywords
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