Sequence and expression of transcripts of the human T-cell receptor β- chain genes
- 1 December 1984
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 312 (5994) , 521-524
- https://doi.org/10.1038/312521a0
Abstract
T lymphocytes can produce mRNAs from the first or second constant region of the T-cell antigen receptor β-chain. A 1.3-kilobase (kb) transcript encoding the mature protein contains V, J and one of the two C region sequences, but does not always contain D sequences. A 1.0-kb mRNA, found mainly in immature T cells, does not contain V sequences and can result from transcription that initiates upstream from an unrearranged J element.Keywords
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