Site-Specific Recombination Between Homologous Chromosomes in Drosophila

17 May 1991

journal article
other
Published by American Association for the Advancement of Science (AAAS) in Science

Vol. 252 (5008) , 958-961
https://doi.org/10.1126/science.2035025

Abstract

The ability to mark a cell and its descendants genetically so that the resulting cell clone can be distinguished from neighboring cells facilitates studies in animal biology and development. A method of generating clones by inducing homologous mitotic recombination in Drosophila with a site-specific yeast recombinase is described. This method allows for frequent mosaicism after mitotic exchange is induced at predefined sites in the genome.

Keywords

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