A polymorphism of the gamma-chain of mouse C4 controlled by the S region of the major histocompatibility complex.
Open Access
- 1 September 1980
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 125 (3) , 1178-1182
- https://doi.org/10.4049/jimmunol.125.3.1178
Abstract
Three phenotypes of the gamma-chain of mouse C4 have been detected by a modification of the two-dimensional O'Farrell technique. Strains carrying the H-2s, H-2p, H-2f and H-2ja haplotypes had chains with pI 7.4 (gamma 1). Strains with H-2k, H-2q, H-2d, H-2r, H-2b, H-2u, and H-2w7 had gamma-chains with pI 6.9 (gamma 2), and strains carrying a wild-derived haplotype had gamma chains with pI 6.5 (gamma 3). The genes controlling this polymorphism were mapped in the S region of the H-2 complex by using congenic strains.This publication has 12 references indexed in Scilit:
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