Cerebral Pathology in Rodents in Endemic Typhus and Rocky Mountain Spotted Fevers

Abstract
The brains of various wild rodents inoculated with passage strains of endemic typhus and of Rocky Mountain spotted fever present after suitable intervals a characteristic reaction similar to that seen in man and guinea pigs in these diseases. Those showing reactions in typhus are Peromyscus polionotus, P. leucopus, P. eremicus, P. maniculatus, Reithrodontomys sp., Mus musculus and Rattus norvegicus; in spotted fever in M. musculus, Microtus pennsylyanicus and occasionally in Peromyscus gossypinus. Maximum reactions in white mice in typhus appear 14-16 days after inoculation.