Synthesis of 2,3-benzo-fused 1-oxacephems

Abstract
4-Acetoxyazetidin-2-one (2) reacted with salicylaldehyde and 2-hydroxyphenyl ketones to give tricyclic hydroxy-amine products, and the reaction with ethyl 2-hydroxyphenylacetate was employed in the synthesis of a 2,3-benzo-fused ethoxycarbonyl 1-oxa analogue of the cephems.

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