Phagocytosis of Unopsonized Zymosan by Human Monocyte-Derived Macrophages: Maturation and Inhibition by Mannan
- 1 November 1985
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Leukocyte Biology
- Vol. 38 (5) , 655-658
- https://doi.org/10.1002/jlb.38.5.655
Abstract
Human monocyte-derived macrophages phagocytosed zymosan in the absence of serum opsonins. The capacity to ingest zymosan developed after the cells were cultured in vitro for 3 days and was inhibited completely by mannan. We conclude that human monocyte-derived macrophages phagocytose unopsonized zymosan predominantly via mannose receptors.Keywords
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