Surgical Treatment for Partial Children and Epilepsy Among Norwegian Adolescents

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Abstract
Summary: We conducted a retrospective longitudinal self‐controlled study of 64 patients aged 4–19 years treated with resective surgery for partial epilepsy from 1952 to 1988. Approximately 60% of patients experienced >95% reduction in seizure frequency, and 70% hadworth while improvement of at least 75% reduction. Seizure relief was more frequent among patients who under‐went operation after 1978, and significant differences by time period of operation were noted for those with temporal lobe excisions and patients with normal tissue histology. The region of resection and the age at treatment did not provide significant information with respect toseizure outcome. Postresection electrocorticography(ECoG) and EEG of the first postoperative year predicted later seizure outcome. Small neurologic deficits weremore common among patients resected in the temporallobe than in patients resected in the frontal lobe. Half ofthe patients with preoperative unilateral focal activity anda third of those with bilateral focal activity had normal EEG postoperatively. One fourth had discontinued antiepileptic drug (AED) therapy. As expected, long‐termmortality was significantly higher than the mortality of the general population. Seven patients died during followup. Two male patients committed suicide.