MEASUREMENT OF 24-HOUR WHOLE-BODY RETENTION OF TC-99M HEDP BY A GAMMA-CAMERA

  • 1 January 1981
    • journal article
    • research article
    • Vol. 22  (6) , 542-545
Abstract
Measurement of 24-h whole-body retention [WBR] of 99mTc-HEDP [diphosphonate], using a shadow-shield, whole-body monitor, was a sensitive measure of skeletal metabolism and of value in the diagnosis of metabolic bone disease. A new method of measuring the retention, using a .gamma.-camera [GC] with a scanning (fishtail) collimator and patient placed at 2.3 m distance, was evaluated in 18 patients undergoing routine bone scans. The patients had WBR measured using the whole-body monitor (WBM); the 2 methods correlated well, yielding a regression line GC% = -0.82 + 0.98 WBM%, r = 0.975, P < 0.001. The limitations to, and repeatability of, the GC measurements are discussed. This work shows that measurements of WBR can be obtained in any nuclear medicine department possessing a GC with a suitable collimator.

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