Mutastein, a new inhibitor of adhesive-insoluble glucan synthesis by glucosyltransferases of Streptococcus mutans.

Abstract
Mutastein, a new inhibitor of glucosyltransferases of S. mutans, was isolated from cultural broth of Aspergillus terreus M3328. Mutastein was a heat-stable protein and was sensitive to pronase digestion. Formation adhesive water-insoluble glucans (which are involved in dental caries induction) of S. mutans was specifically inhibited by mutastein.

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