Clinical Experience With Subanesthetic Ketamine

Abstract
Forty thermally injured patients received 150 intramuscular (I.M.) administrations of sub-anesthetic ketamine for debridement and dressing changes. Satisfactory analgesia lasting approximately 15 minutes, complete amnesia, and good operating conditions were achieved. Tolerance to ketamine developed in all patients receiving more than two exposures. Recovery was prompt, with resumption of oral alimentation in approximately 1 hour. Side effects were minimal, and no major complications occurred.

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