Abstract
Medical errors are in the news almost daily, frequently after patients have experienced ineffective and unsafe protocols. As a result, patients and family members lose trust in the healthcare system. Nursing practice is changing almost daily with advances in nursing research and improvements in technology and practice. Reading, understanding, and managing these large amounts of information have become difficult for most nurses and organizations. This article provides an historical background for evidence-based practice and methods for assimilating research into practice. Systematic reviews and other decision-making models are discussed using specific questions for establishing policy guidelines. Evidence-based practice encompasses implementing the best-known practices into the clinical setting using a scientific approach. As a result, safe, high-quality, and cost-effective care will be more likely to occur consistently.