Most Virus-specific Polypeptides in Cells Productively Infected with Marek's Disease Virus or Herpesvirus of Turkeys Possess Cross-reactive Determinants
Open Access
- 1 April 1983
- journal article
- Published by Microbiology Society in Journal of General Virology
- Vol. 64 (4) , 961-965
- https://doi.org/10.1099/0022-1317-64-4-961
Abstract
Summary Most virus-specific polypeptides in cells productively infected with Marek's disease virus (MDV) or herpesvirus of turkeys (HVT) possess cross-reactive antigenic determinants, although the two viruses have very little DNA homology. The cross-reactivity appeared to be more evident when [35S]methionine-labelled polypeptides were immunoprecipitated than when the [3H]glucosamine-labelled polypeptides were immunoprecipitated, suggesting that the glycoproteins of MDV and HVT may be less related in structure than other proteins. The major cross-reactive glycoproteins excreted into the culture mediums of MDV- and HVT-infected cells had molecular weights of 64000 (gp64) and 56000 (gp56) respectively.Keywords
This publication has 0 references indexed in Scilit: