EFFECT OF FLURBIPROFEN ON HERPES-SIMPLEX KERATITIS IN RABBITS
- 1 January 1980
- journal article
- research article
- Vol. 19 (3) , 267-270
Abstract
The rabbit ocular model was used to determine if flurbiprofen, a new non-steroidal anti-inflammatory agent, caused exacerbation of herpes simplex virus (HSV) infection. Acute ocular HSV infections treated with flurbiprofen (0.1%) or dexamethasone (0.1%) drops 4 times a day for 10 days were similar in severity and duration as measured by corneal lesions, conjunctivitis and corneal clouding. Eyes receiving placebo healed more rapidly than eyes treated with either anti-inflammatory drug. Flurbiprofen appears comparable with dexamethasone in clinical exacerbation of acute ocular HSV infection.This publication has 1 reference indexed in Scilit: