“Plasmacytoid T Cells” in Castlemanʼs Disease Immunohistologic Phenotype
- 1 February 1987
- journal article
- research article
- Published by Wolters Kluwer Health in The American Journal of Surgical Pathology
- Vol. 11 (2) , 109-113
- https://doi.org/10.1097/00000478-198702000-00004
Abstract
Plasmacytoid T cells in two cases of Castleman's disease were stained with a panel of monoclonal antibodies to hematopoietic cell-associated antigens, using an immunoperoxidase technique on frozen sections. The immunohistologic phenotype of these cells was T4/Leu-3 +, HLA-DR+, Tl/Leu-1–, T3/Leu-4–, T8/Leu-2–, Til/Leu-5–, Bl–, B2–, Leu-14–, Ig–, CALLA–, OKM1–, Leu-Ml–. In contrast to plasma cells of B lineage, plasmacytoid T cells were T200+, T10–. The phenotype was similar to that of two previously reported lymphomas of plasmacytoid T cells. Plasmacytoid T cells appear to be a unique subset of lymphoid cells, whose function remains to be established.This publication has 0 references indexed in Scilit: