N, N′-carbonyldiimidazole-induced diketopiperazine formation in aqueous solution in the presence of adenosine-5′-monophosphate

Abstract
3′(2′)-O-glycyl-adenosine-5′-monophosphate is an intermediate in the conversion of N-[imidazolyl-(1)-carbonyl]-glycine to diketopiperazine in the presence of adenosine-5′-monophosphate. The significance of these observations to prebiotic chemistry is discussed.