Abstract
Gray extrapolates from circuit models of psychopathology to propose neural substrates for the contents of consciousness. I raise three concerns: (1) knowledge of synaptic arrangements may be inadequate to fully support his model; (2) latent inhibition deficits in schizophrenia, a focus of this and related models, are complex and deserve replication; and (3) this conjecture omits discussion of the neuropsychological basis for the contents of the unconscious.