CuBr-Catalyzed Efficient Alkynylation of sp3 C−H Bonds Adjacent to a Nitrogen Atom
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- 1 September 2004
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 126 (38) , 11810-11811
- https://doi.org/10.1021/ja0460763
Abstract
A simple and effective catalytic method to construct propargylamine was developed by using copper bromide and tert-BuOOH via a combination of sp3 C-H bond and sp C-H bond activations followed by C-C bond formation.Keywords
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