Oxygen reactive radicals production in cell culture by okadaic acid and their implication in protein synthesis inhibition
- 1 October 1999
- journal article
- research article
- Published by SAGE Publications in Human & Experimental Toxicology
- Vol. 18 (10) , 634-639
- https://doi.org/10.1191/096032799678839473
Abstract
Okadaic acid (OA), a diarrhetic shellfish toxin is a potent promoter of tumours in mouse skin and a specific inhibitor of protein phosphatases 1 and 2A. Recently it has been shown that OA inhibited...Keywords
This publication has 21 references indexed in Scilit:
- INHIBITION OF PROTEIN SYNTHESIS IN A CELL-FREE SYSTEM AND VERO CELLS BY OKADAIC ACID, A DIARRHETIC SHELLFISH TOXINJournal of Toxicology and Environmental Health, 1996
- Characterization of natural toxins with inhibitory activity against serine/threonine protein phosphatasesToxicon, 1994
- Structurally different members of the okadaic acid class selectively inhibit protein serine/threonine but not tyrosine phosphatase activityToxicon, 1992
- Diarrhoeic shellfish toxins in Adriatic Sea mussels evaluated by an ELISA methodToxicon, 1992
- Regulation of Ca2+ -dependent K+ -channel activity in tracheal myocytes by phosphorylationNature, 1989
- Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kineticsBiochemical Journal, 1988
- Diarrhetic shellfish toxinsTetrahedron, 1985
- Identification of okadaic acid as a toxic component of a marine dinoflagellate Prorocentrum lima.NIPPON SUISAN GAKKAISHI, 1982
- Isolation and structural elucidation of the causative toxin of the diarrhetic shellfish poisoning.NIPPON SUISAN GAKKAISHI, 1982
- Okadaic acid, a cytotoxic polyether from two marine sponges of the genus HalichondriaJournal of the American Chemical Society, 1981