Role of Interleukin-6 in the Control of Acute and Chronic Giardia lamblia Infections in Mice
Open Access
- 1 March 2003
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 71 (3) , 1566-1568
- https://doi.org/10.1128/iai.71.3.1566-1568.2003
Abstract
In this study, we investigated the role of interleukin-6 (IL-6) in Giardia lamblia infections in mice. Elevated IL-6 expression was found in wild-type mice 15 days postinfection. Furthermore, IL-6-deficient mice controlled infections only slowly although normal immunoglobulin A production was observed. Thus, IL-6 is necessary for early control of acute G. lamblia infections.Keywords
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