Relaxation and related 1H nmr studies on "asperlin." Configuration and conformation of the epoxypropyl side-chain
- 1 May 1985
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 63 (5) , 1009-1012
- https://doi.org/10.1139/v85-171
Abstract
Monoselective and biselective spin-lattice relaxation rates, together with nOe [nuclear Overhauser enhancement] experiments were used to examine the configuration and conformation of the epoxypropyl side-chain of asperlin [a metabolite of Aspergillus nidulans] (1) in benzene solution. The oxirane ring is trans, and 1 is the 6R,7S diastereomer. In the most probably conformation of the side-chain about the C.sbd.5,C.sbd.6 bond, H-5 and H-6 are anti.This publication has 1 reference indexed in Scilit:
- Synthesis and stereochemistry of 2-pyrone derivatives related to some fungal metabolitesCanadian Journal of Chemistry, 1978