Phagocytosis of Staphylococci Seen in Peripheral Blood Smear

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Abstract
A FEW ORGANISMS capable of causing septicemia invade the host in such massive and overwhelming numbers that they are visible intracellularly and extracellularly in the ordinary peripheral blood smear. Five organisms have been known to produce such fulminating infection, i.e.,Pasteurella pestis, Neisseria meningitidis, Bacillus anthracis,Staphylococcus, and Streptococcus. We have recently encountered a case of overwhelming staphylococcal septicemia in which this phenomenon was noted and we believe that the circumstances are unusual enough to report. Report of a Case History.—A 19-year-old woman bank teller was admitted to the Charles V. Chapin Hospital on Oct. 24, 1961, stuporous, febrile, and complaining of severe headache. Three weeks before admission she suffered from coryza accompanied by severe headaches and chills. She received an antihistaminic drug, improved, and was able to return to work. Ten days prior to admission she again suffered from severe headache, malaise, anorexia, and fever. She received parenteral penicillin

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