The synthesis of some peptides containing glutamic acid

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Abstract
For use in experiments concerning the mechanism of the assimilation of glutamic acid by Staphylococcus aureus (Rowlands et al. 1957), the following new peptides were synthesized: L-valyl-L-glutamic acid, L-valyl-[alpha]-L-glutamyl-L-valine, L-leucyl-[alpha]-L-glutamyl-L-leucine, [alpha]-L-glutamyl-[alpha]-L-glutamyl-L-glutamlc acid. or-L-Glutamyl-L-alanine was prepared by an alternative route. When gamma-glutamyl peptides are synthesized through benzyloxycarbonyl-ganna-glutamyl azide some a products may occur in the crude material (as found by Sachs and Brand, 1954), but subsequent recrystallization will usually eliminate the a-isomer.