Hydropic Degeneration of Epidermal Keratinocytes

Abstract
Report of 2 patients with brownish, ill-defined macules on their fingers, in one case also on elbows and knees. Light microscopy revealed identical changes in both cases: scattered, swollen, vacuolated, clear keratinocytes in the suprabasal epidermis and horny layer. Electron microscopy showed alterations which were interpreted as hydropic degeneration of keratinocytes.

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