Specific cross-protection between Schistosoma bovis and S. haematobium induced by highly irradiated infections in mice
- 1 July 1989
- journal article
- research article
- Published by Wiley in Parasite Immunology
- Vol. 11 (4) , 341-349
- https://doi.org/10.1111/j.1365-3024.1989.tb00672.x
Abstract
Summary Significant levels of resistance against Schistosoma haematobium challenge were developed by mice exposed to highly irradiated (20 krad) cercariae of the homologous species (46–53%) or of the closely related species, S. hovis (34–56%) but not of S. mansoni (– 6–28%). This ability to cross-protect reflects the phylogenetic relationships between these species; S. mansoni and S. bovis, as well as S. mansoni and S. haematobium, failed to cross-protect. The cross-protection demonstrated between S. bovis and S. haematobium in mice was non-reciprocal.Keywords
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