Improved Synthesis of 5,11,17,23,29-Penta-t-butylcalix[5]arene-31,32,33,34,35-pentol and Immobilization of the Conformation by O-Alkylation

Abstract
The synthetic method of the title compound was improved to 16.1% yield. The 1H NMR studies established that the oxygen-through-the-annulus rotation is not inhibited by the butyl group but inhibited by the bulkier octyl group.