EFFECT OF LOW CONCENTRATIONS OF HALOTHANE ON THE OXYGEN ELECTRODE

Publisher Website
Google Scholar
Abstract
The effect of low concentrations of halothane dissolved in saline (.apprx. 0.34% halothane) on the O2 electrode was examined using a multi-wire Clark type electrode, consisting of 8 Pt wires, each of 15 .mu.m tip diameter. On the 1st exposure of the day to saline equilibrated with halothane in 10% O2 or air, the output of the O2 electrode increased by 40% over 56 min. On the 2nd and subsequent exposures the increase in output was much less, but was still 10% greater than the correct values. After immersing the electrode overnight in saline without halothane, the high sensitivity to halothane was present again next morning, even if neither membrane nor electrolyte was changed. [Pt electrodes are used for blood gas analysis in man and animals. Halothane interferes with Pt electrode blood gas measurements].

This publication has 1 reference indexed in Scilit: