The Water-Balance Principle of Crustacean Eye-Stalk Extracts

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Abstract
Eye-stalks of the brackish water-crab, Carcinus moenas, and of the fresh-water crayfish, Potamobius fluviatilis, were extracted according to the pharmacopoeia! method for the extraction of posterior pituitary glands. Injection of such eye-stalk extracts resulted in a temporary increase in the body water of frogs. The increase produced by the extract of one eye-stalk of Carcinus was approximately equal to that produced by the injection of 20 milliunits pitocin ( = oxytocic fraction of mammalian posterior pituitary extract). The crustacean eye-stalk extracts had no significant oxytocic, chloruretic, or antidiuretic effect.

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