IV. Ineffectiveness of Certain Essential Nutrients in Prevention of Tooth Decay in Cotton Rat Molars

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Abstract
A variety of tests was made to determine if superabundant amts. of essential nutrients or opt. amts. of these nutrients from differ -ent sources would alter the initiation anddevelopment of carious lesions in caries-susceptible cotton rats after tooth development was almost complete. Negative results were obtained in all cases indicating that initiation and development of carious lesions in teeth formed before the beginning of the exptl. period were not influenced by additional amts. of the known nutrients tested. The ration described by Keyes for production on carious lesions in hamsters resulted in very poor growth and a low rate of carious lesions in the cotton rat. A supplement of 8% dried brewer''s yeast to the purified ration produced good growth and permitted a slight reduction in the dental caries experience of cotton rats.

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