Amantadine Small-Particle Aerosol: Generation and Delivery to Man
- 1 July 1979
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 161 (3) , 350-354
- https://doi.org/10.3181/00379727-161-40551
Abstract
An aerosol generator suitable for administration of a small-particle aerosol of amantadine for treatment of influenza A infection in man is described. As currently operated, the usual daily recommended oral dose of amantadine of 120-200 mg can be given in 8-10 h of inhalation of the aerosol. Limited clinical study indicates the safety and probable efficacy of the treatment method.This publication has 2 references indexed in Scilit:
- Continuous aerosol therapy system using a modified Collison nebulizerJournal of Clinical Microbiology, 1977
- Therapeutic Effects of Ribavirin Given by the Intraperitoneal or Aerosol Route Against Influenza Virus Infections in MiceAntimicrobial Agents and Chemotherapy, 1976