Toxicology and Pharmacological Action ofAnabaena flos-aquaeToxin
- 14 February 1975
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 187 (4176) , 542-544
- https://doi.org/10.1126/science.803708
Abstract
Calves, rats, ducks, and goldfish given lethal oral doses of bacteria-free lyophilized cell suspensions of toxicAnabaena flos-aquaedied as a result of respiratory arrest. Experiments with selected animals and pharmacological preparations showed that the main effect of the toxin was production of a sustained postsynaptic depolarizing neuromuscular blockade.Keywords
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- Letters to the EditorJournal of Pharmacy and Pharmacology, 1949