Abstract
The families of 11 probands with Pick''s disease [a pre-senile dementia], as determined by histopathological examination, were investigated by interview and acquisition of medical records. The estimated morbid risk was 0.25 .+-. 0.08 for parents and 0.07 .+-. 0.07 for siblings of probands. Associations between morbid risk and age, sex and age of onset were presented. Data needed for genetic counseling were including.

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