Unilateral Adenectomy in the Cretin Rat.

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Abstract
Degree of compensatory hypertrophy of various glands in the cretin rat (prepared by feeding thiouracil to pregnant adult rats) is compared with that in euthyroid controls of the same age. Per cent renal compensatory hypertrophy in the cretin of either sex is equal to that of the normal animal. However, compensatory responses appear to be greatly lessened in adrenals, virtually abolished in thyroids, and markedly increased in testes and ovaries of cretin rats. Correlations of various glandular responses with pituitary cytology are considered.

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