Allergic Aspergillus Sinusitis

1 September 1993

journal article
research article
Published by American Medical Association (AMA) in JAMA Otolaryngology–Head & Neck Surgery

Vol. 119 (9) , 1042-1043
https://doi.org/10.1001/archotol.1993.01880210136019

Abstract

AllergicAspergillussinusitis seems to be diagnosed more frequently. This entity has definite similarities to allergic bronchopulmonary aspergillosis (ABPA) serologically and histopathologically. Rosenberg et al¹have suggested clinical and immunologic criteria for ABPA that includes: (1) bronchoconstriction, (2) eosinophilia, (3) immediate skin reactivity toAspergillusantigen, (4) precipitin antibodies againstAspergillusantigen, (5) elevated IgE, (6) history of pulmonary infiltrates, and (7) central bronchiectasis. If all seven criteria are fulfilled, the diagnosis of ABPA is considered "definite." A "probable" diagnosis is made if six of seven criteria exist. The clinical picture of allergicAspergillus sinusitisand ABPA, however, is not strictly limited toAspergillusspecies.Bipolaris,²Curvularia,³andExserohilum⁴species have been cultured from individuals with sinusitis that is clinically and histopathologically indistinguishable from allergicAspergillussinusitis. Serologic evaluation is also similar in that total IgE is elevated, with demonstrable fungus-specific IgE and precipitin IgG antibod

Keywords

This publication has 2 references indexed in Scilit:

Allergic fungal sinusitis due to Curvularia lunata
Human Pathology, 1987
Clinical and Immunologic Criteria for the Diagnosis of Allergic Bronchopulmonary Aspergillosis
Annals of Internal Medicine, 1977