THE INDEPENDENCE OF SPONTANEOUS GASTRO-INTESTINAL MOTILITY AND BLOOD SUGAR LEVELS

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Abstract
Intravenous injection of glucose (71 experiments on 9 normal dogs, 33 on 3 double vagotomized dogs), did not modify gastric, terminal ileum or colonic motility, thus failing to sustain the theory that spontaneous motility of the empty stomach is inversely related to the blood sugar level. The spontaneous hypo-glycemia occurring several hrs. after glucose administration was without constant effect on motility of stomach, ileum or colon. Glucose, cane sugar or lactose introduced into the empty stomach produced gastric inhibition in the normal or vagotomized dog. This inhibition was apparently not related to the production of hypergly-cemia but appeared to be a reflex from the duodenum. Carbohydrates introduced into the duodenum led to a similar gastric inhibition.

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