Abstract
Of 131 patients who received 1 or more renal transplants over a 12 yr period, 12 patients showed evidence of extensive small vessel calcification on routine bone surveys. All patients developed symptomatology directly attributable to advanced secondary hyperparathyroidism. All patients eventually showed evidence of extensive bone disease. Progressive small-vessel calcification in the renal homotransplant patient may underlie secondary hyperparathyroidism.