Diurnal variations in radiosensitivity of mouse intestine
- 1 April 1975
- journal article
- Published by Oxford University Press (OUP) in The British Journal of Radiology
- Vol. 48 (568) , 312-314
- https://doi.org/10.1259/0007-1285-48-568-312
Abstract
Crypts in the mouse small intestine show a diurnal rhythm in radiosensitivity and are most sensitive in the middle of the dark period, when mitotic activity in the crypt is high. Analysis of crypt survival on a cellular basis shows that the changes in cryptogenic cell radiosensitivity are dose-modifying between 1,000 and 1,450 rads gamma rays such that the DO value varies between 85 rads and 140 rads.Keywords
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