ABSENCE OF NUCLEAR PROGESTERONE RECEPTOR IN LH RELEASING HORMONE NEURONES IN LAYING HENS
- 1 August 1984
- journal article
- Published by Bioscientifica in Journal of Endocrinology
- Vol. 102 (2) , R5-R7
- https://doi.org/10.1677/joe.0.102r005
Abstract
Using a double immunohistochemical technique, LH releasing hormone (LHRH) neurones and 110kDa nuclear progesterone receptor were localized in the hypothalamus of the laying hen. Nuclear progesterone receptor was widely distributed throughout the hypothalamus, occurring in the preoptic, septal, anterior and basal areas. The region where progesterone receptor was revealed in nuclei of neurones overlapped that containing LHRH neurones. However, LHRH cell bodies did not contain progesterone nuclear receptor. It is concluded that the positive feedback action of progesterone on LH release is not mediated by a genomic mechanism within the LHRH neurone.Keywords
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